Research News April
Veterinary Neuroanatomy and Clinical Neurology, 2d ed. Saunders ; pp Fly catching in the cavalier King Charles spaniel. Update Cerebral palsy case study presentation Mitral Valve Disease. Humans with MVP [mitral valve prolapse] tend to have shortened platelet survival times and thromboembolic episodes primarily in the retinal and cerebral circulation.
Thromboembolic events in the retinal ore cerebral circulation may be involved in the disturbances described in the breed as 'episodic falling' and 'fly catching'. Neurological diseases of the Cavalier King Charles spaniel.
J Small Animal Practice, June46 6: However, it is more likely that this is a compulsive disorder Luescher Classically, the dog acts as if watching, and then catching, a fly. Some may behave as if their ears or feet are irritated, and some may also chase their tail. In severe cases, the dog is occupied in the behaviour almost full time.
Compulsive disorders are compared with obsessivecompulsive disorders in humans and are poorly understood; it is presumed that there is a neurochemical imbalance Luescher Diagnosis is typically made on the basis of clinical history and elimination of other behavioural, medical and neurological disorders.
Ideally the owner should make a video of the behaviour. Management of compulsive disorders has been reviewed by Luescher In principle the behavioural therapy is to train the dog with positive reinforcement, rewarding it with attention or a small treat, to perform a desirable behaviour that is incompatible with the compulsive behaviour, such as lying with its head on the floor between the paws.
As soon as the compulsive behaviour is seen then the dog is immediately distracted and instructed to perform the desirable behaviour.
The reward can be progressively delayed so that the dog has to remain in the chosen position for increasingly longer times before the reward is given. If drugs are given then it can take four weeks before an effect is seen and they must be continued for at least three weeks after achieving the desired effect before attempting to withdraw them over a minimum of three weeks.
High protein diets, such as those with high meat content, tend to make compulsive behaviours worse and conversion to a low protein diet can result in improvement in signs Brownalthough in some dogs this may be only temporary.
Clinicopathological abnormalities included severely increased serum lipase activity, immeasurably high serum trypsin-like immunoreactivity and mild hypocalcaemia. Canine pancreatic lipase immunoreactivity cPLI was intended to be measured, however, the sample got lost.
Ultrasonography revealed a hypoechoic pancreas with small amounts of peripancreatic fluid and hyperechogenic mesentery. Acute pancreatitis AP was diagnosed and the dog recovered with appropriate therapy within 48 hours.
Clomipramine, a selective serotonin reuptake inhibitor SSRI for alleviating signs of separation anxiety had been given for seven weeks.
Two similar, albeit less severe, episodes associated with previous courses of clomipramine had occurred eight months earlier that responded to discontinuing clomipramine and supportive care. As SSRIs are associated with AP in human beings and no other trigger could be identified, we conclude that clomipramine should be considered as a potential cause when investigating causes for AP in susceptible breeds or other dogs presenting with compatible clinical signs.
Clinical recovery and normalization of the dopamine transporter binding after clomipramine treatment.
Treatment was started with the tricyclic antidepressant clomipramine 2. After 2 months of medication that resulted in clinical improvement, the DAT binding regained normal values. Alex Gough, Alison Thomas. Serotonin 2A receptor, serotonin transporter and dopamine transporter alterations in dogs with compulsive behaviour as a promising model for human obsessive-compulsive disorder.
Neuroimaging, online 27 Jan Fifteen normally behaving dogs were used as reference group. Significantly lower 5-HT2A receptor radioligand availability in frontal and temporal cortices bilateral was observed.
Interestingly, both increased and decreased DAT ratios were observed. Finally, significantly lower subcortical perfusion and hypo thalamic SERT availability were observed in the compulsive dogs. This study provides evidence for imbalanced serotonergic and dopaminergic pathways in the pathophysiology of compulsions in dogs.
The similarities with the altered neurotransmission in human OCD provide construct validity for this non-induced, natural canine model, suggesting its usefulness for future investigations of the pathophysiology of human OCD as well as the effectiveness of psychopharmacological interventions.
This behavior is a nonspecific sign and may be the consequence of several conditions. The objectives of our prospective clinical study were to characterize ELS behavior in dogs and to examine the extent to which it may be a sign of an underlying gastrointestinal GI pathology as opposed to a primarily behavioral concern.
Nineteen dogs presented with ELS were included in the licking group and 10 healthy dogs were assigned to a control group. Behavioral, physical, and neurological examinations were performed before a complete evaluation of the GI system.Aug 22, · Cerebral palsy is the leading cause of childhood disability affecting function and development.
The incidence of the condition has not changed in more than 4 decades, despite significant advances in the medical care of neonates.
Cerebral Palsy -Birth Time Medical Negligence - Cerebral palsy (CP) is a general term for a group of permanent, movement problems that do not get worse over time. They cause physical disability, mainly in the areas of body movement.
It occurs due to medical negligence at the time of birth. Case Study: Preschool-Age Child with Cerebral Palsy / Diplegia / Constipation Development of this content was partially supported by a grant from HRSA (D09HP).
Microsoft Word - Case Study - Preschool Age Child Cerebral Palsy Diplegia vetconnexx.com Tobacco smoking and pregnancy is related to many effects on health and reproduction, in addition to the general health effects of tobacco.A number of studies have shown that tobacco use is a significant factor in miscarriages among pregnant smokers, and that it contributes to a number of other threats to the health of the fetus..
Ideally, women should not smoke before, during or after.
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